Motif ID: FOX{F1,F2,J1}.p2

Z-value: 0.716


Transcription factors associated with FOX{F1,F2,J1}.p2:

Gene SymbolEntrez IDGene Name
FOXF1 2294 forkhead box F1
FOXF2 2295 forkhead box F2
FOXJ1 2302 forkhead box J1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXF2chr6_+_13900680.328.3e-02Click!
FOXJ1chr17_-_74137370-0.328.6e-02Click!
FOXF1chr16_+_865441040.251.8e-01Click!


Activity profile for motif FOX{F1,F2,J1}.p2.

activity profile for motif FOX{F1,F2,J1}.p2


Sorted Z-values histogram for motif FOX{F1,F2,J1}.p2

Sorted Z-values for motif FOX{F1,F2,J1}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{F1,F2,J1}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_9745847 2.991 GLP2R
glucagon-like peptide 2 receptor
chr11_-_102826433 1.237 NM_002427
MMP13
matrix metallopeptidase 13 (collagenase 3)
chr11_-_102668892 1.230 NM_001145938
NM_002421
MMP1

matrix metallopeptidase 1 (interstitial collagenase)

chr11_-_102668822 1.190 MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr6_-_131321868 1.176 NM_001252660
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr1_+_152486977 1.007 NM_019060
CRCT1
cysteine-rich C-terminal 1
chr2_-_165424993 0.926 GRB14
growth factor receptor-bound protein 14
chr1_-_24469571 0.867 NM_021258
IL22RA1
interleukin 22 receptor, alpha 1
chr1_+_171154387 0.823 NM_001460
FMO2
flavin containing monooxygenase 2 (non-functional)
chr11_-_121986800 0.769 NM_001001786
BLID
BH3-like motif containing, cell death inducer
chr7_-_122635753 0.742 NM_016945
TAS2R16
taste receptor, type 2, member 16
chr14_-_55650348 0.707 DLGAP5
discs, large (Drosophila) homolog-associated protein 5
chr7_+_134576187 0.692 CALD1
caldesmon 1
chr11_-_71752099 0.681 NUMA1
nuclear mitotic apparatus protein 1
chr7_+_77469446 0.677 NM_001127357
NM_001127359
NM_020432
PHTF2


putative homeodomain transcription factor 2


chr4_-_39033981 0.671 NM_024943
TMEM156
transmembrane protein 156
chrX_-_65259839 0.623 NM_001100431
NM_001184830
NM_001184831
NM_007268
VSIG4



V-set and immunoglobulin domain containing 4



chr1_-_93342706 0.613 NM_001252271
FAM69A
family with sequence similarity 69, member A
chr3_+_98451537 0.582 NM_006100
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr4_-_186456580 0.571 NM_001114107
NM_014476
PDLIM3

PDZ and LIM domain 3

chr4_-_21950373 0.564 NM_147182
KCNIP4
Kv channel interacting protein 4
chr17_-_5138049 0.550 NM_207103
SCIMP
SLP adaptor and CSK interacting membrane protein
chr5_+_147691988 0.549 NM_032566
SPINK7
serine peptidase inhibitor, Kazal type 7 (putative)
chr11_-_63933204 0.548 MACROD1
MACRO domain containing 1
chr1_+_150122415 0.548 PLEKHO1
pleckstrin homology domain containing, family O member 1
chr1_-_205391180 0.528 NM_001001552
NM_001199050
NM_001199051
NM_001199052
LEMD1



LEM domain containing 1



chr14_+_32798478 0.526 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chr17_-_29641068 0.526 EVI2B
ecotropic viral integration site 2B
chr5_+_81601165 0.525 NM_001017971
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr7_+_129906702 0.520 NM_001869
CPA2
carboxypeptidase A2 (pancreatic)
chr8_+_55528626 0.519 NM_006269
RP1
retinitis pigmentosa 1 (autosomal dominant)
chr4_+_36285643 0.518 NM_001170700
DTHD1
death domain containing 1
chr1_-_161193375 0.517 NM_001643
APOA2
apolipoprotein A-II
chr1_+_171060017 0.504 NM_001002294
NM_006894
FMO3

flavin containing monooxygenase 3

chr15_-_80207597 0.485 NM_001100879
ST20
suppressor of tumorigenicity 20
chr7_-_143059144 0.481 NM_014690
FAM131B
family with sequence similarity 131, member B
chr19_+_56687388 0.475 NM_001145546
NM_033106
GALP

galanin-like peptide

chr10_-_121296044 0.459 NM_002925
RGS10
regulator of G-protein signaling 10
chr2_+_210444154 0.456 MAP2
microtubule-associated protein 2
chrY_+_14813159 0.450 NM_004654
USP9Y
ubiquitin specific peptidase 9, Y-linked
chr9_+_78505514 0.449 NM_001190482
NM_006200
PCSK5

proprotein convertase subtilisin/kexin type 5

chr3_-_165555252 0.445 NM_000055
BCHE
butyrylcholinesterase
chr17_-_7082559 0.441 ASGR1
asialoglycoprotein receptor 1
chr20_-_1309809 0.436 NM_080489
SDCBP2
syndecan binding protein (syntenin) 2
chr21_+_30517897 0.430 C21orf7
chromosome 21 open reading frame 7
chr11_-_115375065 0.430 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr7_-_142659397 0.426 KEL
Kell blood group, metallo-endopeptidase
chr15_-_34610928 0.423 NM_005135
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr12_-_80307690 0.416 NM_001143886
PPP1R12A
protein phosphatase 1, regulatory subunit 12A
chr13_-_46756291 0.415 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_+_209602164 0.410 NM_001104548
MIR205HG
MIR205 host gene (non-protein coding)
chr12_-_76425375 0.407 NM_007350
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr3_-_165555167 0.406 BCHE
butyrylcholinesterase
chr1_+_150480486 0.405 NM_001202858
NM_004425
NM_022664
ECM1


extracellular matrix protein 1


chr17_-_7082654 0.400 NM_001197216
NM_001671
ASGR1

asialoglycoprotein receptor 1

chr19_-_49016418 0.399 NM_001080434
LMTK3
lemur tyrosine kinase 3
chr11_-_63933493 0.388 NM_014067
MACROD1
MACRO domain containing 1
chr20_-_22566092 0.381 NM_153675
FOXA2
forkhead box A2
chr1_-_168106810 0.381 GPR161
G protein-coupled receptor 161
chr11_+_60260250 0.372 NM_001164470
NM_017716
MS4A12

membrane-spanning 4-domains, subfamily A, member 12

chr4_+_71587674 0.370 NM_001037442
NM_014961
RUFY3

RUN and FYVE domain containing 3

chr18_+_61575203 0.368 SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr19_+_18391252 0.368


chr10_-_90712510 0.365 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr2_-_31637553 0.364 XDH
xanthine dehydrogenase
chr11_-_67450536 0.363 RPL37
ribosomal protein L37
chrX_-_38079980 0.363 NM_001170750
NM_001170751
NM_001170752
NM_006307
SRPX



sushi-repeat containing protein, X-linked



chr1_-_168106727 0.358 GPR161
G protein-coupled receptor 161
chr10_+_102732285 0.353 NM_001203244
NM_017893
SEMA4G

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G

chr10_+_22540986 0.350 LOC100130992
uncharacterized LOC100130992
chr2_+_169929009 0.349 NM_001142270
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr17_-_29641094 0.344 NM_006495
EVI2B
ecotropic viral integration site 2B
chr11_-_114466471 0.344 NM_001077639
NM_017678
FAM55D

family with sequence similarity 55, member D

chr1_+_150122095 0.343 NM_016274
PLEKHO1
pleckstrin homology domain containing, family O member 1
chr12_-_53045947 0.334 NM_000423
KRT2
keratin 2
chr16_-_86542463 0.332 LOC400550
uncharacterized LOC400550
chr6_-_105627857 0.331 NM_022361
POPDC3
popeye domain containing 3
chr3_-_149086884 0.329 TM4SF1
transmembrane 4 L six family member 1
chr11_+_33060962 0.328 NM_018393
TCP11L1
t-complex 11 (mouse)-like 1
chr19_-_33360641 0.327 NM_001126335
NM_001243036
NM_014270
SLC7A9


solute carrier family 7 (glycoprotein-associated amino acid transporter light chain, bo,+ system), member 9


chr7_-_140624280 0.325 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr1_+_150122246 0.323 PLEKHO1
pleckstrin homology domain containing, family O member 1
chr19_+_18496966 0.320 NM_004864
GDF15
growth differentiation factor 15
chr14_-_94789641 0.320 NM_001756
SERPINA6
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr5_-_36301999 0.318 NM_001161429
NM_145000
RANBP3L

RAN binding protein 3-like

chr15_-_40600065 0.317 PLCB2
phospholipase C, beta 2
chr10_+_70847817 0.315 NM_002727
SRGN
serglycin
chr1_+_172389827 0.315 NM_139240
C1orf105
chromosome 1 open reading frame 105
chr6_+_26501448 0.314 NM_001732
BTN1A1
butyrophilin, subfamily 1, member A1
chr6_-_112575766 0.312 NM_001105206
NM_001105207
NM_001105208
NM_001105209
NM_002290
LAMA4




laminin, alpha 4




chr1_-_168106535 0.302 GPR161
G protein-coupled receptor 161
chr7_-_87342569 0.299 NM_000927
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr15_-_40599974 0.298 PLCB2
phospholipase C, beta 2
chr11_+_33061560 0.295 NM_001145541
TCP11L1
t-complex 11 (mouse)-like 1
chr13_-_61989209 0.295 PCDH20
protocadherin 20
chr6_-_112575880 0.295 LAMA4
laminin, alpha 4
chr22_-_33402648 0.293 NM_003490
NM_133633
SYN3

synapsin III

chr4_-_89978117 0.293 NM_014883
FAM13A
family with sequence similarity 13, member A
chr9_-_21305311 0.290 NM_002169
IFNA5
interferon, alpha 5
chr12_-_99038705 0.289 IKBIP
IKBKB interacting protein
chr8_-_72459891 0.288


chr7_-_142659412 0.288 NM_000420
KEL
Kell blood group, metallo-endopeptidase
chr11_-_27723061 0.283 NM_170733
BDNF
brain-derived neurotrophic factor
chr17_-_29641087 0.283 EVI2B
ecotropic viral integration site 2B
chr6_-_112575708 0.282 LAMA4
laminin, alpha 4
chr14_+_74551655 0.282 NM_001024674
LIN52
lin-52 homolog (C. elegans)
chr8_+_1952875 0.282 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr13_+_98086315 0.282 NM_021033
RAP2A
RAP2A, member of RAS oncogene family
chr2_+_33661392 0.281 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr8_-_15095791 0.281 NM_139167
SGCZ
sarcoglycan, zeta
chr3_-_71180061 0.279 NM_001244815
FOXP1
forkhead box P1
chr7_+_123249076 0.278 NM_080928
ASB15
ankyrin repeat and SOCS box containing 15
chr7_+_128312345 0.276 NM_001012454
NM_001128926
FAM71F2

family with sequence similarity 71, member F2

chr11_-_59612925 0.274 NM_005142
GIF
gastric intrinsic factor (vitamin B synthesis)
chr10_+_97759847 0.273 NM_001001732
NM_001159747
CC2D2B

coiled-coil and C2 domain containing 2B

chr20_+_44036940 0.273 DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr18_+_60382617 0.271 NM_194449
PHLPP1
PH domain and leucine rich repeat protein phosphatase 1
chr3_-_167191808 0.267 NM_006217
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr6_-_30655671 0.267 NM_133471
PPP1R18
protein phosphatase 1, regulatory subunit 18
chr5_-_39203061 0.266 FYB
FYN binding protein
chr15_+_80390757 0.265 NM_001242919
ZFAND6
zinc finger, AN1-type domain 6
chr4_-_152149042 0.263 NM_001243349
SH3D19
SH3 domain containing 19
chr6_-_128239741 0.262 NM_001164687
THEMIS
thymocyte selection associated
chr7_+_134233848 0.260 NM_001080538
AKR1B15
aldo-keto reductase family 1, member B15
chr5_-_132161863 0.259 NM_133456
SHROOM1
shroom family member 1
chr13_-_99910548 0.258 NM_001098200
NM_005292
GPR18

G protein-coupled receptor 18

chr22_+_37309618 0.258 NM_000395
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr1_-_161193190 0.253 APOA2
apolipoprotein A-II
chr5_-_180076599 0.253 FLT4
fms-related tyrosine kinase 4
chr1_-_197036350 0.252 NM_001994
F13B
coagulation factor XIII, B polypeptide
chr15_-_40600025 0.250 PLCB2
phospholipase C, beta 2
chr15_+_43477315 0.250 NM_012142
CCNDBP1
cyclin D-type binding-protein 1
chr19_-_46148606 0.249 NM_001193268
EML2
echinoderm microtubule associated protein like 2
chr3_-_20053618 0.248 NM_001252657
PP2D1
protein phosphatase 2C-like domain containing 1
chr1_+_84630374 0.245 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr10_-_5045967 0.243 NM_001135241
AKR1C2
aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chr8_+_74903563 0.242 NM_001195797
NM_015364
LY96

lymphocyte antigen 96

chr8_+_120079423 0.241 NM_006438
COLEC10
collectin sub-family member 10 (C-type lectin)
chr1_-_186649421 0.241 NM_000963
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr4_+_155484131 0.236 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr18_+_29769986 0.235 NM_005925
MEP1B
meprin A, beta
chr3_-_71179715 0.234 FOXP1
forkhead box P1
chr2_-_192711651 0.233 SDPR
serum deprivation response
chr4_-_123377471 0.233 NM_000586
IL2
interleukin 2
chr2_-_165478357 0.232 NM_004490
GRB14
growth factor receptor-bound protein 14
chr12_-_96390002 0.232 NM_002108
HAL
histidine ammonia-lyase
chr3_+_156392204 0.231 NM_015508
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr1_+_192544856 0.230 NM_002922
RGS1
regulator of G-protein signaling 1
chr4_-_111119752 0.228 NM_001130721
NM_024090
ELOVL6

ELOVL fatty acid elongase 6

chr9_-_21368005 0.228 NM_006900
IFNA1
IFNA13
interferon, alpha 1
interferon, alpha 13
chr18_+_61370193 0.227 NM_080475
SERPINB11
serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene)
chr3_+_143692166 0.226 NM_001134470
C3orf58
chromosome 3 open reading frame 58
chr16_+_56225301 0.226 GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr5_-_13944588 0.226 NM_001369
DNAH5
dynein, axonemal, heavy chain 5
chr2_+_179184970 0.225 NM_145739
OSBPL6
oxysterol binding protein-like 6
chr1_+_74701070 0.224 NM_015978
TNNI3K
TNNI3 interacting kinase
chr4_-_70826712 0.224 NM_001891
CSN2
casein beta
chr3_-_150920946 0.221 NM_013308
GPR171
G protein-coupled receptor 171
chr7_+_37723378 0.220


chr9_+_136287119 0.220 NM_139025
NM_139026
NM_139027
ADAMTS13


ADAM metallopeptidase with thrombospondin type 1 motif, 13


chr1_+_20915440 0.220 NM_001785
CDA
cytidine deaminase
chr1_+_169337432 0.219 BLZF1
basic leucine zipper nuclear factor 1
chr16_+_81040120 0.217 CENPN
centromere protein N
chr11_-_5526833 0.212 NM_001005567
OR51B5
HBE1
olfactory receptor, family 51, subfamily B, member 5
hemoglobin, epsilon 1
chr1_-_103496768 0.211 COL11A1
collagen, type XI, alpha 1
chr14_+_37126772 0.210 NM_006194
PAX9
paired box 9
chr5_-_10308167 0.209 NM_138809
CMBL
carboxymethylenebutenolidase homolog (Pseudomonas)
chr15_+_40509628 0.209 NM_001128628
NM_001128629
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr8_-_108510094 0.209 NM_001146
NM_001199859
ANGPT1

angiopoietin 1

chr1_+_116654375 0.208 NM_152367
MAB21L3
mab-21-like 3 (C. elegans)
chr1_-_240775388 0.208 GREM2
gremlin 2
chr6_+_108882104 0.207 FOXO3
forkhead box O3
chr20_+_16728997 0.206 NM_020157
OTOR
otoraplin
chr14_+_65877309 0.205 NM_004480
NM_178155
NM_178156
FUT8


fucosyltransferase 8 (alpha (1,6) fucosyltransferase)


chr13_+_41885340 0.204 NM_001110798
NM_018527
NM_024561
NAA16


N(alpha)-acetyltransferase 16, NatA auxiliary subunit


chr1_-_169703178 0.204 NM_000450
SELE
selectin E
chr7_+_28725597 0.203 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr16_+_28699878 0.203 NM_001199142
EIF3C
eukaryotic translation initiation factor 3, subunit C
chr3_+_156392369 0.202 TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr12_+_9142136 0.196 NM_005810
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr2_-_192711923 0.195 NM_004657
SDPR
serum deprivation response
chr19_-_51141301 0.194 NM_032298
SYT3
synaptotagmin III
chr1_+_203444955 0.194 PRELP
proline/arginine-rich end leucine-rich repeat protein
chr1_-_231560789 0.194 NM_022051
EGLN1
egl nine homolog 1 (C. elegans)
chr2_-_215896809 0.193 NM_015657
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr1_+_65730423 0.193 NM_014787
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr5_-_36241684 0.193 NADKD1
NAD kinase domain containing 1
chr17_+_58755158 0.192 NM_001099432
NM_017679
BCAS3

breast carcinoma amplified sequence 3

chr12_+_79258588 0.191 SYT1
synaptotagmin I
chr9_+_136287443 0.189 ADAMTS13
ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr5_+_60933635 0.188 NM_173667
C5orf64
chromosome 5 open reading frame 64
chr12_+_100041527 0.188 NM_153364
FAM71C
family with sequence similarity 71, member C
chr10_+_70847857 0.188 SRGN
serglycin
chr13_+_109248499 0.187 NM_015011
MYO16
myosin XVI
chr6_-_127780534 0.186 NM_014702
KIAA0408
KIAA0408
chr13_-_45775174 0.185 NM_198404
KCTD4
potassium channel tetramerisation domain containing 4
chr22_+_50609159 0.185 NM_001160300
NM_052839
PANX2

pannexin 2

chr6_-_76203256 0.185 NM_015687
FILIP1
filamin A interacting protein 1
chrX_-_15288172 0.185 NM_001031739
NM_001168530
NM_024087
ASB9


ankyrin repeat and SOCS box containing 9


chr9_-_77503009 0.184 NM_017662
TRPM6
transient receptor potential cation channel, subfamily M, member 6

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
5.89 2.44e-04 GO:0008206 bile acid metabolic process
2.30 4.20e-02 GO:0008202 steroid metabolic process
2.13 4.81e-02 GO:0019932 second-messenger-mediated signaling

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.44 1.06e-04 GO:0044459 plasma membrane part
1.27 6.60e-04 GO:0005886 plasma membrane
1.27 8.25e-04 GO:0071944 cell periphery

Nothing significant found in function category.